Rheum4Science - Complement Pathways
The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. Rheum4Science will enable the learner to:
- Examine the underlying biology and clinical research methodology necessary for the knowledgeable practice of rheumatology.
- Understand the immunology elements and mechanisms integral to the pathophysiology of rheumatic diseases and drug mechanisms of action.
- Apply an understanding of clinical research methods to interpret primary literature in rheumatology and patient care scenarios.
Rheumatology fellows in training, medical students, residents, practicing rheumatologists, and other rheumatology health care providers interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.
Upon completion of this activity, participants should be able to do the following:
- Compare the three complement pathways – understanding how both their unique and shared components function in normal immune response.
- Describe the effects of complement activation on innate and adaptive immunity in both normal and pathologic states.
- Discuss consequences of complement component deficiencies, including associations with known diseases.
- Explain how complement pathways are regulated and give examples of disorders that arise from regulatory dysfunction.
This activity is complimentary.