Activity InformationRheum2Learn 2.0 is case-based fundamental clinical rheumatology education for residents. Each interactive activity includes three patient cases that focus on the care and assessment of individuals with rheumatologic diseases. In this activity, explore diverse patient presentations with widespread or regional musculoskeletal pain. Participants will learn to differentiate clinical patterns and approaches to diagnosis and treatment for conditions such as polymyalgia rheumatica (PMR), fibromyalgia, and joint hypermobility syndromes. This activity is part of a series. See the other activities in the series below.Rheum2Learn 2.0: Crystalline ArthritisRheum2Learn 2.0: Infectious ArthritisRheum2Learn 2.0: Inflammatory MyopathiesRheum2Learn 2.0: Musculoskeletal ExaminationRheum2Learn 2.0: OsteoporosisRheum2Learn 2.0: OsteoarthritisRheum2Learn 2.0: Pediatric RheumatologyRheum2Learn 2.0: Rheumatic Manifestations of Systemic DiseaseRheum2Learn 2.0: Rheumatoid ArthritisRheum2Learn 2.0: Sjögren’s DiseaseRheum2Learn 2.0: SpondyloarthritisRheum2Learn 2.0: Systemic Lupus ErythematosusRheum2Learn 2.0: Systemic SclerosisRheum2Learn 2.0: Systemic VasculitisRegistration is complimentary.Target AudienceResidents in training who may provide care for patients with rheumatic diagnoses in primary care, inpatient, critical care, and other clinical contexts.The activity may also be of interest to medical students, fellows in training, advanced practice providers, practicing physicians, and other health care professionals who seek to strengthen their clinical knowledge of rheumatic diseases.Learning ObjectivesUpon completion of this activity, participants should be able to:Compare and contrast polymyalgia rheumatica (PMR) from other causes of musculoskeletal pain  Recognize how PMR presents and understand risk for GCA with PMRDemonstrate how to taper prednisone in treating PMRIdentify a patient with joint hypermobility using the hypermobility questionnaire and Beighton scoreDistinguish between hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS)Determine need for referrals in patients with suspected hEDSDescribe the key clinical manifestations of fibromyalgiaOutline mimickers of fibromyalgia and ways to distinguish them from fibromyalgiaDiscuss non-pharmacologic and pharmacologic treatments for fibromyalgia CE & MOC InformationThis activity is not eligible for CME/MOC.Acknowledgement of Commercial SupportNo commercial support was provided for this activity.Educational Activity PoliciesSee ACR educational activity policies, including the online enduring activity refund policy.