Activities

Activity Overview

The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. The Rheum4Science: Immunology Series provides a progressive, clinically focused foundation in immunology for emerging rheumatology clinicians.

Participants will explore innate and adaptive immune mechanisms and their relevance to rheumatologic disease, strengthening diagnostic insight and clinical decision‑making.

Registration is complimentary.

Rheum4Science Series

This activity is part of a series. See the other activities in the series below.

Rheum4Science Interactive Modules

Rheum4Science – Clinical Research Methodology

Rheum4Science – Immunopathogenesis of Rheumatic Disease


Target Audience

Rheumatology fellows in training. This activity may also be of interest to medical students, residents, practicing rheumatologists, and other rheumatology health care professionals interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.


Learning Objectives

Upon completion of this activity, participants should be able to:

  • Explain the core organization and principles of the immune system, including recognition, activation, regulation, and memory in health and disease

  • Differentiate innate and adaptive immune responses, including their key cells, mediators, effector mechanisms, and timing

  • Describe how immune responses are initiated and shaped, including pattern recognition, antigen processing and presentation, and immune signaling pathways

  • Summarize the roles of key immune cells and mediators, including dendritic cells, neutrophils, cytokines, complement, T cells, B cells, and antibodies

  • Explain how immune responses are anatomically organized, including lymphoid organs, immune compartments, and cellular trafficking

  • Recognize mechanisms of immune dysregulation that contribute to autoimmunity, autoinflammatory disease, and immune‑mediated tissue injury

  • Apply foundational immunologic concepts to clinical reasoning in rheumatology, supporting diagnostic interpretation and therapeutic decision‑making


CE & MOC Information

This activity is not eligible for credit.


Acknowledgement of Commercial Support

No commercial support was provided for this activity.


Educational Activity Policies

See ACR educational activity policies, including the online enduring activity refund policy.

Activity Overview

The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. Rheum4Science interactive modules teach the underlying immunology and clinical research methodology necessary for the knowledgeable practice of rheumatology.

Learn how to identify the immune components of preclinical rheumatoid arthritis (RA) and the implications for the treatment of RA.

Registration is complimentary.

Rheum4Science Series

This activity is part of a series. See the other activities in the series below.

Rheum4Science Interactive Modules

Rheum4Science – Clinical Research Methodology

Rheum4Science – Immunopathogenesis of Rheumatic Disease


Target Audience

Rheumatology fellows in training. This activity may also be of interest to medical students, residents, practicing rheumatologists, and other rheumatology health care professionals interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.


Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify the immune components of preclinical rheumatoid arthritis(RA)

  • Describe how preclinical RA becomes clinical disease

  • Discuss implications for the treatment of RA


CE & MOC Information

This activity is not eligible for credit.


Acknowledgement of Commercial Support

No commercial support was provided for this activity.


Educational Activity Policies

See ACR educational activity policies, including the online enduring activity refund policy.

Activity Overview

The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. Rheum4Science interactive modules teach the underlying immunology and clinical research methodology necessary for the knowledgeable practice of rheumatology.

In this activity, learn about data collection and distribution, including the different research variables and how to select and interpret the best measures of central tendency and dispersion.

Registration is complimentary.

Rheum4Science Series

This activity is part of a series. See the other activities in the series below.

Rheum4Science Interactive Modules

Rheum4Science – Clinical Research Methodology

Rheum4Science – Immunopathogenesis of Rheumatic Disease


Target Audience

Rheumatology fellows in training. This activity may also be of interest to medical students, residents, practicing rheumatologists, and other rheumatology health care professionals interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.


Learning Objectives

Upon completion of this activity, participants should be able to:

  • Differentiate types of variables (continuous, ordinal, nominal, binary, categorical)

  • Recognize various data distributions

  • Select the best measures of central tendency and dispersion for reporting common data distributions

  • Interpret measures of central tendency and dispersion


CE & MOC Information

This activity is not eligible for credit.


Acknowledgement of Commercial Support

No commercial support was provided for this activity.


Educational Activity Policies

See ACR educational activity policies, including the online enduring activity refund policy.

Activity Overview

The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. Rheum4Science interactive modules teach the underlying immunology and clinical research methodology necessary for the knowledgeable practice of rheumatology.

Randomized controlled trials (RCT) are an integral part of assessing efficacy. Learn when an RCT research study design is appropriate, whether to trust the results, and how to interpret the results.

Registration is complimentary.

Rheum4Science Series

This activity is part of a series. See the other activities in the series below.

Rheum4Science Interactive Modules

Rheum4Science – Clinical Research Methodology

Rheum4Science – Immunopathogenesis of Rheumatic Disease


Target Audience

Rheumatology fellows in training. This activity may also be of interest to medical students, residents, practicing rheumatologists, and other rheumatology health care professionals interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.


Learning Objectives

Upon completion of this activity, participants should be able to:

  • Recognize scenarios in which a randomized controlled trial (RCT) would be appropriate

  • Determine whether to trust the results of an RCT (assessment of internal validity)

  • Accurately interpret the results of an RCT

  • Determine whether it is appropriate to apply the results of a study to a patient (assessment of external validity)


CE & MOC Information

This activity is not eligible for credit.


Acknowledgement of Commercial Support

No commercial support was provided for this activity.


Educational Activity Policies

See ACR educational activity policies, including the online enduring activity refund policy.

Activity Overview

The creation of the Rheum4Science program grew out of the conviction that teaching science is important for rheumatologists in training and that adult learners benefit from a variety of resources and formats. Rheum4Science interactive modules teach the underlying immunology and clinical research methodology necessary for the knowledgeable practice of rheumatology.

This activity focuses on cohort studies, a type of observational study.  Learn about the defining strengths and limitations of cohort studies and how to apply the results of a cohort study to patient scenarios.

Registration is complimentary.

Rheum4Science Series

This activity is part of a series. See the other activities in the series below.

Rheum4Science Interactive Modules

Rheum4Science – Clinical Research Methodology

Rheum4Science – Immunopathogenesis of Rheumatic Disease


Target Audience

Rheumatology fellows in training. This activity may also be of interest to medical students, residents, practicing rheumatologists, and other rheumatology health care professionals interested in strengthening their understanding of basic scientific principles and clinical research methodology relevant to the field of rheumatology.


Learning Objectives

Upon completion of this activity, participants should be able to:

  • Recognize a cohort study

  • Delineate the strengths and limitations of a cohort study

  • Identify clinical questions that could be best answered using a cohort study

  • Recognize potential pitfalls encountered in cohort studies, and strategies to address these

  • Accurately interpret analytic approaches used in cohort studies

  • Apply the results of a cohort study to patient scenarios


CE & MOC Information

This activity is not eligible for credit.


Acknowledgement of Commercial Support

No commercial support was provided for this activity.


Educational Activity Policies

See ACR educational activity policies, including the online enduring activity refund policy.