Activity OverviewRheum2Learn 2.0 is case-based fundamental clinical rheumatology education for residents. Each interactive activity includes three patient cases that focus on the care and assessment of individuals with rheumatologic diseases.In this activity, learn how to identify clinical manifestations, interpret test results, and develop a differential diagnosis and treatment plan for patients with inflammatory myopathies.  Topics include myositis, abnormal hyperCKemia (CK), dermatomyositis, and anti-synthetase syndrome.Rheum2Learn 2.0 Series This activity is part of a series. See all activities in the series below.Rheum2Learn 2.0: Crystalline ArthritisRheum2Learn 2.0: Infectious ArthritisRheum2Learn 2.0: Inflammatory MyopathiesRheum2Learn 2.0: Musculoskeletal DisordersRheum2Learn 2.0: Musculoskeletal ExaminationRheum2Learn 2.0: OsteoporosisRheum2Learn 2.0: OsteoarthritisRheum2Learn 2.0: Pediatric RheumatologyRheum2Learn 2.0: Rheumatic Manifestations of Systemic DiseaseRheum2Learn 2.0: Rheumatoid ArthritisRheum2Learn 2.0: Sjögren’s DiseaseRheum2Learn 2.0: SpondyloarthritisRheum2Learn 2.0: Systemic Lupus ErythematosusRheum2Learn 2.0: Systemic SclerosisRheum2Learn 2.0: Systemic VasculitisRegistration is complimentary.Target AudienceResidents in training who may provide care for patients with rheumatic diagnoses in primary care, inpatient, critical care, and other clinical contexts.The activity may also be of interest to medical students, fellows in training, advanced practice providers, practicing physicians, and other health care professionals who seek to strengthen their clinical knowledge of rheumatic diseases. Learning ObjectivesUpon completion of this activity, participants should be able to:Differentiate among non-neuromuscular and neuromuscular causes of elevated hyperCKemia (CK) levels Describe clinical history and physical exam to evaluate hyperCKemiaPropose appropriate laboratory studies to evaluate hyperCKemia Recognize when appropriate to refer to neurology and/or rheumatology for evaluationDescribe physical exam maneuvers of the neuromuscular exam to assess weaknessIdentify common skin findings associated with dermatomyositisExplain the role of laboratory, imaging, and pathology in diagnosing dermatomyositisRecognize association of dermatomyositis with malignancy (ovarian cancer) - paraneoplastic, malignancy screeningFormulate a differential for a patient with shortness of breath, cough, and fatigueDescribe clinical features of anti-synthetase syndromeExplain the role of laboratory tests and imaging in diagnosing anti-synthetase syndromeRecognize appropriateness of referral and hospital admissionCE & MOC InformationThis activity is not eligible for CME/MOC.Acknowledgement of Commercial SupportThe project was supported by grant number 1 NU58DP006908-01-00 – Component A: Developing and Disseminating Programs to Build Sustainable Lupus Awareness, Knowledge, Skills and Partnerships. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Department of Health and Human Services, Centers for Disease Control and Prevention.Educational Activity PoliciesSee ACR educational activity policies, including the online enduring activity refund policy.