Cassandra Calabrese is an Assistant Professor at the Cleveland Clinic Lerner College of Medicine of CWRU and holds a dual appointment in the Departments of Rheumatologic and Immunologic Disease and Infectious Disease at the Cleveland Clinic, where she completed a 3-year combined rheumatology and infectious disease fellowship. She also holds an appointment in the Cleveland Clinic Taussig Cancer Center.

Her areas of interest include infection in the setting of immunosuppression, infection prevention and immunizations, rheumatic manifestations of infection, human immunodeficiency virus, COVID-19 and immune related adverse events from checkpoint inhibitor therapy.